2022.01.13|#ergothioneine

【Material Introduction】 Ergothioneine

In this article, we will introduce one of the antioxidants, ergothioneine.

■What is Ergothioneine?

Ergothioneine is a natural compound classified as a rare amino acid derivative. It is produced by certain microorganisms such as some mushrooms, koji molds, and actinomycetes, and humans can only incorporate it into their bodies by consuming these foods.

Structure of Ergothioneine

Ergothioneine is known for its exceptionally strong antioxidant activity. It is said to have up to 30 times higher scavenging ability for reactive oxygen species compared to glutathione, which is the most abundant antioxidant in the human body.

Ergothioneine has recently gained attention as a health component. Interestingly, it has been discovered that there are transporters in human cells specifically designed to uptake ergothioneine, and it has been found that human cells can accumulate ergothioneine in high concentrations. The fact that humans actively utilize ergothioneine, a compound they cannot naturally produce, has been met with great astonishment. Subsequent research has revealed even more surprising aspects of ergothioneine.

■Functions of Ergothioneine

Ergothioneine is the only substance capable of directly eliminating hydroxyl radicals, known as the culprits behind the formation of harmful substances called peroxidized lipids. It has also been found to have an inhibitory effect on various systemic diseases such as neurodegenerative diseases (Alzheimer's and Parkinson's diseases), depression, skin aging, cataracts, and more. While ergothioneine is highly beneficial for the body, it has been observed that its accumulation in cells decreases with age. Consuming it through diet can help suppress various age-related diseases.

Ergothioneine, with its potent and unique antioxidant properties, may hold the key to future aging care!